Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7435.091 | 0.9945 | 0.9809 | 0.5716 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7435.091 | 0.9473 | 0.8193 | 0.5716 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7435.091 | 0.9635 | 0.8741 | 0.5716 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7435.091 | 1.0421 | 1.1498 | 0.5716 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7435.091 | 0.9317 | 0.7672 | 0.5716 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7435.091 | 0.6659 | -0.0181 | 0.5716 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7435.091 | 0.0006 | -1.0000 | 0.5716 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7435.091 | 0.0006 | -1.0000 | 0.5716 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7436.091 | 0.9470 | 0.9147 | 1.2489 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7436.091 | 1.0009 | 1.0014 | 1.2489 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7436.091 | 0.9874 | 0.9798 | 1.2489 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7436.091 | 1.0316 | 1.0504 | 1.2489 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7436.091 | 1.0578 | 1.0920 | 1.2489 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7436.091 | 1.0098 | 1.0157 | 1.2489 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7436.091 | 0.7357 | 0.5641 | 1.2489 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7436.091 | 0.0094 | -0.9524 | 1.2489 | |
| HCC1395 | TNBC | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7436.091 | 0.0076 | -0.9599 | 1.2489 | |
| HCC1419 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7437.091 | 0.9817 | 0.8946 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7437.091 | 1.0255 | 1.1526 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7437.091 | 1.0319 | 1.1924 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7437.091 | 0.9970 | 0.9825 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7437.091 | 1.0129 | 1.0765 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7437.091 | 0.9787 | 0.8778 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7437.091 | 0.8665 | 0.3154 | 0.3419 | |
| HCC1419 | HER2amp | Luminal | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7437.091 | 0.0140 | -1.0000 | 0.3419 |