Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 60 | uM | 12523.143 | 0.6953 | 0.3751 | 0.9700 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 300 | uM | 12523.143 | 0.4451 | -0.1319 | 0.9700 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 1500 | uM | 12523.143 | 0.4138 | -0.1947 | 0.9700 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 12239.143 | 0.8925 | 0.8959 | 2.1267 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 12239.143 | 0.9140 | 0.9172 | 2.1267 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 12239.143 | 0.9025 | 0.9058 | 2.1267 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 12239.143 | 0.8669 | 0.8701 | 2.1267 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 12239.143 | 0.9027 | 0.9060 | 2.1267 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 12239.143 | 0.8398 | 0.8423 | 2.1267 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 12239.143 | 0.4222 | 0.3334 | 2.1267 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 12239.143 | 0.1288 | -0.2372 | 2.1267 | ||
| HCC1806 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 12239.143 | 0.1052 | -0.3065 | 2.1267 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 11849.143 | 0.9802 | 0.9704 | 1.3433 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 11849.143 | 1.0155 | 1.0231 | 1.3433 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 11849.143 | 1.0222 | 1.0329 | 1.3433 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 11849.143 | 1.0605 | 1.0893 | 1.3433 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 11849.143 | 0.9782 | 0.9675 | 1.3433 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 11849.143 | 0.8143 | 0.7164 | 1.3433 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 11849.143 | 0.5638 | 0.3055 | 1.3433 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 11849.143 | 0.3915 | -0.0049 | 1.3433 | ||
| HCC1937 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 11849.143 | 0.3525 | -0.0797 | 1.3433 | ||
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 0.00384 | uM | 11055.143 | 1.0196 | 1.0227 | 1.7215 | ||
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 0.0192 | uM | 11055.143 | 1.0874 | 1.0997 | 1.7215 | ||
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 0.096 | uM | 11055.143 | 1.0563 | 1.0646 | 1.7215 | ||
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 0.48 | uM | 11055.143 | 1.0189 | 1.0219 | 1.7215 |