Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5895.098 | 0.4171 | 0.0729 | 1.4041 | |
| 184A1 | NM | Basal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5895.098 | 0.3867 | 0.0166 | 1.4041 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5896.091 | 0.9665 | 0.9550 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5896.091 | 0.9765 | 0.9686 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5896.091 | 0.9403 | 0.9195 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5896.091 | 0.9535 | 0.9375 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5896.091 | 0.8547 | 0.8011 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5896.091 | 0.4286 | 0.1364 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5896.091 | 0.3965 | 0.0788 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5896.091 | 0.3157 | -0.0734 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 133 | uM | 5896.091 | 0.1903 | -0.3389 | 1.4988 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5896.098 | 0.9546 | 0.9429 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5896.098 | 0.9562 | 0.9449 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5896.098 | 0.9730 | 0.9662 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5896.098 | 0.9399 | 0.9242 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5896.098 | 0.8695 | 0.8330 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5896.098 | 0.6018 | 0.4572 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5896.098 | 0.3823 | 0.0981 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5896.098 | 0.3022 | -0.0516 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5896.098 | 0.1535 | -0.3784 | 1.6038 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5897.091 | 0.9886 | 0.9814 | 1.2296 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5897.091 | 0.9900 | 0.9838 | 1.2296 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5897.091 | 1.0013 | 1.0021 | 1.2296 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5897.091 | 1.0165 | 1.0268 | 1.2296 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5897.091 | 0.9865 | 0.9780 | 1.2296 |