Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9860.012 | 0.2194 | -0.1744 | 1.7144 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9878.012 | 0.9991 | 0.9985 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9878.012 | 1.1320 | 1.2098 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9878.012 | 0.7598 | 0.6034 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9878.012 | 0.3974 | -0.0481 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9878.012 | 0.3048 | -0.2311 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9878.012 | 0.2942 | -0.2525 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9878.012 | 0.2890 | -0.2631 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9878.012 | 0.2257 | -0.3961 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9878.012 | 0.2512 | -0.3418 | 1.2431 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9889.012 | 1.0639 | 1.0927 | 1.3671 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9889.012 | 1.0976 | 1.1409 | 1.3671 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9889.012 | 0.9271 | 0.8922 | 1.3671 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9889.012 | 0.3839 | -0.0070 | 1.3671 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9889.012 | 0.3984 | 0.0201 | 1.3671 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9889.012 | 0.3608 | -0.0512 | 1.3671 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9889.012 | 0.3597 | -0.0532 | 1.3671 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9889.012 | 0.3091 | -0.1526 | 1.3671 | |
| SUM52PE | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9889.012 | 0.2067 | -0.3687 | 1.3671 | |
| T47D | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9897.012 | 0.9704 | 0.8771 | 0.4748 | |
| T47D | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9897.012 | 0.9840 | 0.9332 | 0.4748 | |
| T47D | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9897.012 | 0.9956 | 0.9814 | 0.4748 | |
| T47D | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9897.012 | 0.5281 | -0.4788 | 0.4748 | |
| T47D | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9897.012 | 0.3972 | -0.7139 | 0.4748 | |
| T47D | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9897.012 | 0.3736 | -0.7486 | 0.4748 |