Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7918.012 | 0.1430 | 0.0403 | 2.9753 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7918.012 | 0.0573 | -0.2350 | 2.9753 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7918.012 | 0.0516 | -0.2614 | 2.9753 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7918.012 | 0.2947 | 0.3265 | 2.9753 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7918.012 | 0.2259 | 0.2130 | 2.9753 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7918.012 | 0.0524 | -0.2575 | 2.9753 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7919.04 | 1.0085 | 1.0045 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7919.04 | 0.9826 | 0.9906 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7919.04 | 0.2916 | 0.4382 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7919.04 | 0.0290 | -0.2248 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7919.04 | 0.0272 | -0.2375 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7919.04 | 0.0218 | -0.2811 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7919.04 | 0.0251 | -0.2542 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7919.04 | 0.0272 | -0.2375 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7919.04 | 0.0294 | -0.2217 | 3.7375 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9844.012 | 1.0273 | 1.0238 | 2.2776 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9844.012 | 1.0560 | 1.0484 | 2.2776 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9844.012 | 0.7429 | 0.7553 | 2.2776 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9844.012 | 0.1457 | -0.1416 | 2.2776 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9844.012 | 0.0593 | -0.4214 | 2.2776 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9844.012 | 0.0467 | -0.4790 | 2.2776 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9844.012 | 0.0408 | -0.5088 | 2.2776 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9844.012 | 0.0532 | -0.4485 | 2.2776 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9844.012 | 0.0642 | -0.4010 | 2.2776 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7921.04 | 1.0280 | 1.0727 | 0.7738 |