Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9830.019 | 0.9645 | 0.9625 | 1.9053 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9830.019 | 1.0291 | 1.0304 | 1.9053 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9830.019 | 0.9495 | 0.9463 | 1.9053 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 9830.019 | 0.7247 | 0.6890 | 1.9053 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 9830.019 | 0.5988 | 0.5280 | 1.9053 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 9830.019 | 0.4804 | 0.3612 | 1.9053 | |
| SUM149PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 9830.019 | 0.1789 | -0.1896 | 1.9053 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7918.016 | 0.9822 | 0.9885 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7918.016 | 1.0376 | 1.0238 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7918.016 | 0.9697 | 0.9804 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7918.016 | 1.0087 | 1.0056 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7918.016 | 1.0047 | 1.0030 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7918.016 | 1.0056 | 1.0036 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7918.016 | 0.7343 | 0.8114 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7918.016 | 0.4892 | 0.5903 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7918.016 | 0.0171 | -0.4571 | 3.1190 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7919.016 | 0.9907 | 0.9947 | 3.5497 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7919.016 | 0.9809 | 0.9892 | 3.5497 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7919.016 | 0.9980 | 0.9989 | 3.5497 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7919.016 | 1.0204 | 1.0114 | 3.5497 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7919.016 | 1.0189 | 1.0106 | 3.5497 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7919.016 | 0.9245 | 0.9562 | 3.5497 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7919.016 | 0.9065 | 0.9455 | 3.5497 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7919.016 | 0.7012 | 0.8097 | 3.5497 | |
| SUM159PT | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7919.016 | 0.0306 | -0.2507 | 3.5497 |