Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7857.016 | 1.0034 | 1.0057 | 1.2049 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7857.016 | 0.9896 | 0.9828 | 1.2049 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7857.016 | 1.0064 | 1.0107 | 1.2049 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7857.016 | 0.9337 | 0.8892 | 1.2049 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7857.016 | 0.8925 | 0.8199 | 1.2049 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7857.016 | 0.8496 | 0.7470 | 1.2049 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7857.016 | 0.8156 | 0.6888 | 1.2049 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7857.016 | 0.6577 | 0.4125 | 1.2049 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7860.016 | 0.9781 | 0.9293 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7860.016 | 1.0208 | 1.0680 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7860.016 | 1.0194 | 1.0636 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7860.016 | 1.0118 | 1.0385 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7860.016 | 0.9955 | 0.9854 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7860.016 | 0.9001 | 0.6851 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7860.016 | 0.8402 | 0.5065 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7860.016 | 0.7567 | 0.2707 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7860.016 | 0.4110 | -0.5294 | 0.6145 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9501.024 | 1.0338 | 1.0737 | 0.9185 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9501.024 | 1.0803 | 1.1756 | 0.9185 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9501.024 | 1.0073 | 1.0158 | 0.9185 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9501.024 | 0.9947 | 0.9884 | 0.9185 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9501.024 | 0.9348 | 0.8584 | 0.9185 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 9501.024 | 0.9221 | 0.8311 | 0.9185 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 9501.024 | 0.8542 | 0.6846 | 0.9185 | |
| HCC70 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 9501.024 | 0.7015 | 0.3595 | 0.9185 |