Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7809.016 | 0.8263 | 0.7832 | 1.6622 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7809.016 | 0.7960 | 0.7435 | 1.6622 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7809.016 | 0.3778 | 0.1136 | 1.6622 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7810.016 | 0.9908 | 0.9796 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7810.016 | 1.0314 | 1.0697 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7810.016 | 0.9637 | 0.9198 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7810.016 | 1.0376 | 1.0835 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7810.016 | 1.0817 | 1.1817 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7810.016 | 1.0032 | 1.0071 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7810.016 | 0.9602 | 0.9120 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7810.016 | 0.7980 | 0.5578 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7810.016 | 0.5606 | 0.0537 | 0.9032 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9233.049 | 1.1164 | 1.2124 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9233.049 | 0.9921 | 0.9855 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9233.049 | 1.1191 | 1.2173 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9233.049 | 1.0200 | 1.0367 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9233.049 | 1.0299 | 1.0547 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 9233.049 | 0.9500 | 0.9082 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 9233.049 | 0.9452 | 0.8993 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 9233.049 | 0.9236 | 0.8596 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 9233.049 | 0.8582 | 0.7384 | 1.0911 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7811.044 | 1.0372 | 1.2524 | 0.3073 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7811.044 | 1.0310 | 1.2091 | 0.3073 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7811.044 | 0.9758 | 0.8468 | 0.3073 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7811.044 | 1.0680 | 1.4774 | 0.3073 |