Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10755.143 | 0.9272 | 0.8394 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10755.143 | 0.7245 | 0.3999 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10755.143 | 0.7053 | 0.3590 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10755.143 | 0.7143 | 0.3782 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10755.143 | 0.8091 | 0.5820 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10755.143 | 0.6659 | 0.2751 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10755.143 | 0.5736 | 0.0811 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12070.143 | 1.0365 | 1.0764 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12070.143 | 1.0104 | 1.0218 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12070.143 | 0.9673 | 0.9317 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12070.143 | 0.9491 | 0.8937 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12070.143 | 1.0008 | 1.0018 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12070.143 | 0.8469 | 0.6810 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12070.143 | 0.7150 | 0.4081 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12070.143 | 0.6652 | 0.3057 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12070.143 | 0.5015 | -0.0282 | 0.9561 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12112.143 | 1.0397 | 1.0467 | 1.6893 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12112.143 | 1.0028 | 1.0033 | 1.6893 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12112.143 | 0.9685 | 0.9625 | 1.6893 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12112.143 | 0.9687 | 0.9626 | 1.6893 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 8 | uM | 12112.143 | 0.8469 | 0.8126 | 1.6893 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 40 | uM | 12112.143 | 0.6031 | 0.4826 | 1.6893 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 200 | uM | 12112.143 | 0.5893 | 0.4624 | 1.6893 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 1000 | uM | 12112.143 | 0.5004 | 0.3275 | 1.6893 | |
| HCC1143 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 5000 | uM | 12112.143 | 0.2926 | -0.0337 | 1.6893 |