Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.0213 | uM | 11055.156 | 0.7489 | 0.6556 | 1.5301 | |
| HCC1954 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.107 | uM | 11055.156 | 0.6053 | 0.4406 | 1.5301 | |
| HCC1954 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.533 | uM | 11055.156 | 0.6627 | 0.5284 | 1.5301 | |
| HCC1954 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 2.67 | uM | 11055.156 | 0.6349 | 0.4862 | 1.5301 | |
| HCC1954 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 13.3 | uM | 11055.156 | 0.5315 | 0.3233 | 1.5301 | |
| HCC1954 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 66.7 | uM | 11055.156 | 0.0118 | -0.8901 | 1.5301 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 10996.156 | 1.0610 | 1.2966 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 10996.156 | 1.1058 | 1.5292 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 10996.156 | 0.9286 | 0.6822 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 10996.156 | 0.8054 | 0.2066 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 10996.156 | 0.6036 | -0.3848 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 10996.156 | 0.6586 | -0.2458 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 10996.156 | 0.6464 | -0.2780 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 10996.156 | 0.5897 | -0.4173 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 10996.156 | 0.2626 | -0.9119 | 0.4283 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12192.164 | 1.0147 | 1.0506 | 0.5828 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12192.164 | 0.9344 | 0.7801 | 0.5828 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12192.164 | 0.8767 | 0.5959 | 0.5828 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12192.164 | 0.7608 | 0.2510 | 0.5828 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12192.164 | 0.6249 | -0.1075 | 0.5828 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12192.164 | 0.6074 | -0.1500 | 0.5828 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12192.164 | 0.6358 | -0.0805 | 0.5828 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12192.164 | 0.5744 | -0.2275 | 0.5828 | |
| HCC2185 | TNBC | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12192.164 | 0.3867 | -0.6082 | 0.5828 | |
| HCC3153 | TNBC | Basal A | Everolimus | MTOR | MTOR | 0.000171 | uM | 10937.156 | 1.1039 | 1.1510 | 1.3582 |