Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 5902.074 | 1.0461 | 1.0709 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 5902.074 | 1.0176 | 1.0272 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 5902.074 | 0.9747 | 0.9607 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 5902.074 | 0.9751 | 0.9614 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 5902.074 | 1.0036 | 1.0056 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 5902.074 | 0.9028 | 0.8480 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 5902.074 | 0.5023 | 0.1748 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 5902.074 | 0.1948 | -0.4350 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 5902.074 | 0.1310 | -0.5843 | 1.2939 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 5903.074 | 0.9991 | 0.9982 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 5903.074 | 1.0025 | 1.0046 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 5903.074 | 0.9523 | 0.9109 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 5903.074 | 1.0815 | 1.1515 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 5903.074 | 0.9384 | 0.8849 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 5903.074 | 0.7814 | 0.5892 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 5903.074 | 0.3489 | -0.2505 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 5903.074 | 0.1867 | -0.5815 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 5903.074 | 0.1380 | -0.6843 | 1.0729 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 5904.074 | 1.0640 | 1.1327 | 0.9654 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 5904.074 | 0.9976 | 0.9950 | 0.9654 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 5904.074 | 1.0444 | 1.0920 | 0.9654 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 5904.074 | 1.0138 | 1.0287 | 0.9654 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 5904.074 | 0.9281 | 0.8511 | 0.9654 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 5904.074 | 0.5991 | 0.1763 | 0.9654 | |
| BT-20 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 5904.074 | 0.3375 | -0.3509 | 0.9654 |