Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 7449.091 | 0.4969 | 0.3606 | 1.8158 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7450.091 | 2.7501 | 4.2808 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7450.091 | 2.7625 | 4.3037 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7450.091 | 2.5884 | 3.9824 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7450.091 | 2.6511 | 4.0983 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 7450.091 | 2.6469 | 4.0904 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 7450.091 | 1.6521 | 2.2381 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 7450.091 | 0.8215 | 0.6561 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 13.3 | uM | 7450.091 | 2.5440 | 3.9004 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 7450.091 | 1.5662 | 2.0763 | 1.0419 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7451.091 | 0.9907 | 0.9913 | 2.1415 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7451.091 | 0.9244 | 0.9280 | 2.1415 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7451.091 | 0.9538 | 0.9563 | 2.1415 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7451.091 | 0.8757 | 0.8798 | 2.1415 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 7451.091 | 0.7715 | 0.7719 | 2.1415 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 7451.091 | 0.6794 | 0.6697 | 2.1415 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 7451.091 | 0.6572 | 0.6440 | 2.1415 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 13.3 | uM | 7451.091 | 0.5786 | 0.5491 | 2.1415 | |
| HCC1806 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 7451.091 | 0.4834 | 0.4244 | 2.1415 | |
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7453.091 | 1.0181 | 1.0227 | 1.5914 | |
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7453.091 | 0.9397 | 0.9233 | 1.5914 | |
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7453.091 | 0.9596 | 0.9488 | 1.5914 | |
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7453.091 | 0.9112 | 0.8865 | 1.5914 | |
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 7453.091 | 0.9560 | 0.9442 | 1.5914 | |
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 7453.091 | 0.8741 | 0.8379 | 1.5914 |