Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
AU565
HER2amp
Luminal
Erlotinib
EGFR
ErbB
66.7
uM
5901.091
0.1225 -0.3289 1.9229
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.000171
uM
5902.091
0.9928 0.9876 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.000853
uM
5902.091
0.9499 0.9136 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.00427
uM
5902.091
1.0199 1.0342 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.0213
uM
5902.091
0.9816 0.9684 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.107
uM
5902.091
0.9464 0.9077 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.533
uM
5902.091
0.9053 0.8363 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
2.67
uM
5902.091
0.8506 0.7406 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
13.3
uM
5902.091
0.7911 0.6355 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
66.7
uM
5902.091
0.5780 0.2492 1.1648
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.000171
uM
5903.09
0.9899 0.9782 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.000853
uM
5903.09
0.9962 0.9918 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.00427
uM
5903.09
0.9496 0.8917 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.0213
uM
5903.09
0.9456 0.8831 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.107
uM
5903.09
0.9031 0.7923 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.533
uM
5903.09
0.8264 0.6288 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
2.67
uM
5903.09
0.7331 0.4319 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
13.3
uM
5903.09
0.6400 0.2372 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
66.7
uM
5903.09
0.4319 -0.1899 0.9291
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.0000853
uM
5904.092
1.1326 1.2991 0.8933
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.000427
uM
5904.092
0.9541 0.8975 0.8933
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.00213
uM
5904.092
1.0370 1.0829 0.8933
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.0107
uM
5904.092
1.0019 1.0044 0.8933
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.0533
uM
5904.092
0.9718 0.9370 0.8933
BT-20
TNBC
Basal A
Erlotinib
EGFR
ErbB
0.267
uM
5904.092
0.7511 0.4517 0.8933