Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 5901.091 | 0.1225 | -0.3289 | 1.9229 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 5902.091 | 0.9928 | 0.9876 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 5902.091 | 0.9499 | 0.9136 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 5902.091 | 1.0199 | 1.0342 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 5902.091 | 0.9816 | 0.9684 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 5902.091 | 0.9464 | 0.9077 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 5902.091 | 0.9053 | 0.8363 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 5902.091 | 0.8506 | 0.7406 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 13.3 | uM | 5902.091 | 0.7911 | 0.6355 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 5902.091 | 0.5780 | 0.2492 | 1.1648 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 5903.09 | 0.9899 | 0.9782 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 5903.09 | 0.9962 | 0.9918 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 5903.09 | 0.9496 | 0.8917 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 5903.09 | 0.9456 | 0.8831 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 5903.09 | 0.9031 | 0.7923 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 5903.09 | 0.8264 | 0.6288 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 5903.09 | 0.7331 | 0.4319 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 13.3 | uM | 5903.09 | 0.6400 | 0.2372 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 5903.09 | 0.4319 | -0.1899 | 0.9291 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 5904.092 | 1.1326 | 1.2991 | 0.8933 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000427 | uM | 5904.092 | 0.9541 | 0.8975 | 0.8933 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00213 | uM | 5904.092 | 1.0370 | 1.0829 | 0.8933 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0107 | uM | 5904.092 | 1.0019 | 1.0044 | 0.8933 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0533 | uM | 5904.092 | 0.9718 | 0.9370 | 0.8933 | |
BT-20 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.267 | uM | 5904.092 | 0.7511 | 0.4517 | 0.8933 |