Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 5899.09 | 1.0351 | 1.0675 | 1.0401 | |
| 600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 5899.09 | 0.9893 | 0.9795 | 1.0401 | |
| 600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 5899.09 | 0.9785 | 0.9586 | 1.0401 | |
| 600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 5899.09 | 0.9189 | 0.8439 | 1.0401 | |
| 600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 5899.09 | 0.8779 | 0.7646 | 1.0401 | |
| 600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 5899.09 | 0.8938 | 0.7953 | 1.0401 | |
| 600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 5899.09 | 0.8097 | 0.6327 | 1.0401 | |
| 600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 5899.09 | 0.6998 | 0.4189 | 1.0401 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 5900.092 | 1.1072 | 1.0789 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000427 | uM | 5900.092 | 1.0137 | 1.0104 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00213 | uM | 5900.092 | 1.0056 | 1.0042 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0107 | uM | 5900.092 | 0.9897 | 0.9922 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0533 | uM | 5900.092 | 1.0270 | 1.0204 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.267 | uM | 5900.092 | 0.9770 | 0.9824 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 1.33 | uM | 5900.092 | 0.9815 | 0.9859 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 6.67 | uM | 5900.092 | 0.9125 | 0.9316 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 33.3 | uM | 5900.092 | 0.2473 | 0.1765 | 2.6334 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 5901.091 | 1.0318 | 1.0328 | 1.9229 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 5901.091 | 0.9947 | 0.9944 | 1.9229 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 5901.091 | 0.9794 | 0.9784 | 1.9229 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 5901.091 | 1.0634 | 1.0649 | 1.9229 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 5901.091 | 0.9897 | 0.9892 | 1.9229 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 5901.091 | 1.0024 | 1.0025 | 1.9229 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 5901.091 | 0.8636 | 0.8531 | 1.9229 | |
| AU565 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 5901.091 | 0.4356 | 0.2981 | 1.9229 |