Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7918.007 | 0.0432 | -0.3040 | 2.9756 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7918.007 | 0.0042 | -0.6820 | 2.9756 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7919.043 | 1.0431 | 1.0268 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7919.043 | 1.0193 | 1.0121 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7919.043 | 0.9426 | 0.9631 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7919.043 | 0.9041 | 0.9375 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7919.043 | 0.8247 | 0.8822 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7919.043 | 0.3108 | 0.3841 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7919.043 | 0.1799 | 0.1650 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7919.043 | 0.0584 | -0.1826 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7919.043 | 0.0440 | -0.2526 | 3.1744 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 9844.034 | 1.0222 | 1.0198 | 2.2318 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 9844.034 | 0.9895 | 0.9905 | 2.2318 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 9844.034 | 1.0485 | 1.0429 | 2.2318 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 9844.034 | 0.8761 | 0.8849 | 2.2318 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.138 | uM | 9844.034 | 0.3824 | 0.3000 | 2.2318 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.69 | uM | 9844.034 | 0.0716 | -0.3862 | 2.2318 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 3.45 | uM | 9844.034 | 0.1356 | -0.1830 | 2.2318 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 17.2 | uM | 9844.034 | 0.1224 | -0.2195 | 2.2318 | |
| SUM159PT | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 86.2 | uM | 9844.034 | 0.0146 | -0.6988 | 2.2318 | |
| SUM185PE | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 10146.121 | 1.1312 | 1.2558 | 1.0246 | |
| SUM185PE | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 10146.121 | 1.0522 | 1.1019 | 1.0246 | |
| SUM185PE | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 10146.121 | 1.1597 | 1.3112 | 1.0246 | |
| SUM185PE | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 10146.121 | 0.9842 | 0.9692 | 1.0246 | |
| SUM185PE | TNBC | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 10146.121 | 0.9377 | 0.8783 | 1.0246 |