Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.016 | uM | 9226.002 | 0.2514 | 0.1316 | 2.4245 | |
| HBL-100 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.08 | uM | 9226.002 | 0.2746 | 0.1736 | 2.4245 | |
| HBL-100 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.4 | uM | 9226.002 | 0.2514 | 0.1316 | 2.4245 | |
| HBL-100 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 2 | uM | 9226.002 | 0.3689 | 0.3255 | 2.4245 | |
| HBL-100 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 10 | uM | 9226.002 | 0.4257 | 0.4061 | 2.4245 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7810.002 | 0.9794 | 0.9646 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7810.002 | 1.0481 | 1.0824 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7810.002 | 0.9230 | 0.8668 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7810.002 | 0.7407 | 0.5449 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7810.002 | 0.5315 | 0.1612 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7810.002 | 0.2625 | -0.3671 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7810.002 | 0.2864 | -0.3179 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7810.002 | 0.3006 | -0.2888 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7810.002 | 0.4090 | -0.0732 | 1.1625 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9233.002 | 1.0697 | 1.1493 | 0.9358 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9233.002 | 1.1058 | 1.2269 | 0.9358 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9233.002 | 1.0697 | 1.1493 | 0.9358 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9233.002 | 0.9177 | 0.8245 | 0.9358 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 9233.002 | 0.8138 | 0.6049 | 0.9358 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 9233.002 | 0.3877 | -0.2734 | 0.9358 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 9233.002 | 0.3446 | -0.3593 | 0.9358 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 9233.002 | 0.4504 | -0.1472 | 0.9358 | |
| HCC1143 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 9233.002 | 0.5097 | -0.0266 | 0.9358 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7811.002 | 0.9897 | 0.9586 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7811.002 | 0.9919 | 0.9674 | 0.4929 |