Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13099.174 | 0.2692 | -0.5018 | 0.9441 | |
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13099.174 | 0.3229 | -0.3961 | 0.9441 | |
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13099.174 | 0.4969 | -0.0466 | 0.9441 | |
| HCC1143 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13099.174 | 0.1921 | -0.6515 | 0.9441 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12696.174 | 0.9322 | 0.7891 | 0.6299 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12696.174 | 0.9229 | 0.7608 | 0.6299 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12696.174 | 0.9753 | 0.9221 | 0.6299 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12696.174 | 0.9700 | 0.9056 | 0.6299 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12696.174 | 0.8608 | 0.5765 | 0.6299 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12696.174 | 0.6426 | -0.0088 | 0.6299 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12696.174 | 0.7954 | 0.3905 | 0.6299 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12696.174 | 0.7458 | 0.2555 | 0.6299 | |
| HCC1187 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12696.174 | 0.5372 | -0.2541 | 0.6299 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13538.174 | 0.9942 | 0.9748 | 0.4615 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13538.174 | 0.9963 | 0.9839 | 0.4615 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13538.174 | 0.9929 | 0.9694 | 0.4615 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13538.174 | 1.0108 | 1.0472 | 0.4615 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13538.174 | 0.9853 | 0.9367 | 0.4615 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13538.174 | 0.8541 | 0.4210 | 0.4615 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13538.174 | 0.9125 | 0.6399 | 0.4615 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13538.174 | 0.9595 | 0.8285 | 0.4615 | |
| HCC1395 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13538.174 | 0.9244 | 0.6866 | 0.4615 | |
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12612.174 | 0.9516 | 0.8404 | 0.5962 | |
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12612.174 | 0.9546 | 0.8499 | 0.5962 | |
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12612.174 | 0.9589 | 0.8639 | 0.5962 |