Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13579.174 | 0.9946 | 0.9865 | 0.8018 | |
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13579.174 | 0.9720 | 0.9305 | 0.8018 | |
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13579.174 | 0.9851 | 0.9628 | 0.8018 | |
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13579.174 | 1.0042 | 1.0106 | 0.8018 | |
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13579.174 | 0.6826 | 0.2422 | 0.8018 | |
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13579.174 | 0.3203 | -0.5166 | 0.8018 | |
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13579.174 | 0.4405 | -0.2807 | 0.8018 | |
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13579.174 | 0.1983 | -0.7342 | 0.8018 | |
| BT-20 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13579.174 | 0.0020 | -0.9991 | 0.8018 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13125.174 | 0.9364 | 0.8688 | 0.9685 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13125.174 | 0.9059 | 0.8060 | 0.9685 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13125.174 | 0.9476 | 0.8919 | 0.9685 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13125.174 | 0.9453 | 0.8871 | 0.9685 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13125.174 | 0.9367 | 0.8693 | 0.9685 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13125.174 | 0.8714 | 0.7351 | 0.9685 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13125.174 | 0.9369 | 0.8698 | 0.9685 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13125.174 | 0.9157 | 0.8261 | 0.9685 | |
| BT-474 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13125.174 | 0.8165 | 0.6222 | 0.9685 | |
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13130.174 | 0.9744 | 0.9012 | 0.5126 | |
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13130.174 | 0.9472 | 0.7991 | 0.5126 | |
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13130.174 | 0.9713 | 0.8896 | 0.5126 | |
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13130.174 | 0.9590 | 0.8431 | 0.5126 | |
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13130.174 | 0.9356 | 0.7563 | 0.5126 | |
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13130.174 | 0.8432 | 0.4340 | 0.5126 | |
| BT-483 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13130.174 | 0.9535 | 0.8226 | 0.5126 |