Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9860.017 | 0.1740 | -0.2783 | 1.7158 | |
SUM229PE | TNBC | - | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9860.017 | 0.0868 | -0.5188 | 1.7158 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7923.017 | 0.7937 | 0.3833 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7923.017 | 0.8992 | 0.6880 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7923.017 | 0.7827 | 0.3528 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7923.017 | 0.8053 | 0.4157 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7923.017 | 0.9183 | 0.7457 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7923.017 | 0.5022 | -0.3336 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7923.017 | 0.0745 | -0.9683 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7923.017 | 0.0756 | -0.9675 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7923.017 | 0.0988 | -0.9502 | 0.6267 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9878.017 | 0.9576 | 0.9367 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9878.017 | 1.0379 | 1.0560 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9878.017 | 1.0384 | 1.0567 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9878.017 | 0.9363 | 0.9046 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9878.017 | 0.9855 | 0.9784 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9878.017 | 0.6423 | 0.4395 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9878.017 | 0.3140 | -0.1541 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9878.017 | 0.0492 | -0.7865 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9878.017 | 0.0161 | -0.9071 | 1.3463 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9889.021 | 1.0051 | 1.0073 | 1.4017 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9889.021 | 0.9434 | 0.9185 | 1.4017 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9889.021 | 1.0269 | 1.0382 | 1.4017 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9889.021 | 0.9531 | 0.9326 | 1.4017 | |
SUM52PE | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9889.021 | 0.9339 | 0.9047 | 1.4017 |