Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9402.011 | 0.3777 | -0.8870 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9402.011 | 0.0188 | -1.0000 | 0.3388 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7848.011 | 1.0362 | 1.2201 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7848.011 | 1.0352 | 1.2139 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7848.011 | 0.9958 | 0.9757 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7848.011 | 1.0176 | 1.1049 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7848.011 | 1.0027 | 1.0159 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7848.011 | 0.9638 | 0.7944 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7848.011 | 0.7809 | -0.0327 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7848.011 | 0.4932 | -0.7493 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7848.011 | 0.0245 | -1.0000 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7849.011 | 1.0133 | 1.0489 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7849.011 | 0.9598 | 0.8552 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7849.011 | 0.9902 | 0.9642 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7849.011 | 1.0593 | 1.2223 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7849.011 | 1.0067 | 1.0245 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7849.011 | 0.9362 | 0.7726 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7849.011 | 0.7407 | 0.1549 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7849.011 | 0.3776 | -0.6633 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7849.011 | 0.0205 | -0.9984 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9421.021 | 0.9589 | 0.7872 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9421.021 | 1.1142 | 1.6732 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9421.021 | 1.0179 | 1.0975 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9421.021 | 1.0485 | 1.2711 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9421.021 | 1.0850 | 1.4893 | 0.3726 |