Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7437.074 | 0.1722 | -0.9817 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7437.074 | 0.1722 | -0.9817 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7437.074 | 0.0435 | -0.9995 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7437.074 | 0.0435 | -0.9995 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7437.074 | 0.0383 | -0.9997 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7437.074 | 0.0383 | -0.9997 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7437.074 | 0.0449 | -0.9995 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7437.074 | 0.0449 | -0.9995 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7440.074 | 1.0073 | 1.0307 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7440.074 | 1.0073 | 1.0307 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7440.074 | 0.9431 | 0.7692 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7440.074 | 0.9431 | 0.7692 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7440.074 | 0.9749 | 0.8965 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7440.074 | 0.9749 | 0.8965 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7440.074 | 0.6882 | -0.0849 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7440.074 | 0.6882 | -0.0849 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7440.074 | 0.2488 | -0.8912 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7440.074 | 0.2488 | -0.8912 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7440.074 | 0.1314 | -0.9714 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7440.074 | 0.1314 | -0.9714 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7440.074 | 0.0407 | -0.9975 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7440.074 | 0.0407 | -0.9975 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7440.074 | 0.0324 | -0.9985 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7440.074 | 0.0324 | -0.9985 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7440.074 | 0.0356 | -0.9981 | 0.4778 |