Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14218.189 | 0.0594 | -0.7678 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14218.189 | 0.0107 | -0.9373 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14218.189 | 0.0063 | -0.9583 | 1.3111 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14931.189 | 0.9782 | 0.9301 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14931.189 | 0.9810 | 0.9389 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14931.189 | 0.9938 | 0.9801 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14931.189 | 0.9196 | 0.7464 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14931.189 | 0.9796 | 0.9343 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14931.189 | 0.5953 | -0.1356 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14931.189 | 0.0188 | -0.9968 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14931.189 | 0.0309 | -0.9928 | 0.6183 | |
| MDA-MB-157 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14931.189 | 0.0268 | -0.9943 | 0.6183 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14269.189 | 0.9982 | 0.9932 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14269.189 | 0.9800 | 0.9236 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14269.189 | 1.0202 | 1.0788 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14269.189 | 1.0225 | 1.0880 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14269.189 | 0.9752 | 0.9051 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14269.189 | 0.7732 | 0.2164 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14269.189 | 0.1742 | -0.9318 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14269.189 | 0.0799 | -0.9849 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14269.189 | 0.0781 | -0.9855 | 0.5173 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14619.189 | 0.9772 | 0.9642 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14619.189 | 0.9591 | 0.9357 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14619.189 | 0.9690 | 0.9514 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14619.189 | 0.9341 | 0.8962 | 1.2787 |