Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7862.042 | 0.0100 | -0.9459 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7863.018 | 0.9496 | 0.9512 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7863.018 | 1.0100 | 1.0095 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7863.018 | 0.3797 | 0.2597 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7863.018 | 0.3063 | 0.1368 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7863.018 | 0.1258 | -0.2568 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7863.018 | 0.1252 | -0.2585 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7863.018 | 0.1274 | -0.2521 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7863.018 | 0.0414 | -0.5629 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7863.018 | 0.0139 | -0.7408 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7864.042 | 0.9807 | 0.9738 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7864.042 | 1.0149 | 1.0201 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7864.042 | 1.0220 | 1.0296 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7864.042 | 1.0602 | 1.0805 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7864.042 | 0.2536 | -0.2079 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7864.042 | 0.1170 | -0.5303 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7864.042 | 0.1180 | -0.5274 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7864.042 | 0.0479 | -0.7429 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7864.042 | 0.0181 | -0.8667 | 1.4812 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7865.018 | 0.6722 | 0.4331 | 1.1920 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7865.018 | 1.3565 | 1.5830 | 1.1920 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7865.018 | 0.4803 | 0.0811 | 1.1920 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7865.018 | 1.0248 | 1.0415 | 1.1920 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7865.018 | 0.3261 | -0.2188 | 1.1920 | |
| LY2 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7865.018 | 0.3211 | -0.2290 | 1.1920 |