Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12379.152 | 1.0213 | 1.0814 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12379.152 | 0.6708 | -0.0590 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12379.152 | 0.0145 | -0.9993 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12379.152 | 0.0158 | -0.9992 | 0.5297 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10938.152 | 0.9227 | 0.8376 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10938.152 | 0.8837 | 0.7559 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10938.152 | 0.9137 | 0.8187 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10938.152 | 0.8542 | 0.6942 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10938.152 | 0.9607 | 0.9174 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10938.152 | 0.7647 | 0.5078 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10938.152 | 0.6041 | 0.1764 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10938.152 | 0.0109 | -0.9829 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10938.152 | 0.0110 | -0.9826 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12333.152 | 0.9180 | 0.7807 | 0.7371 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12333.152 | 0.9283 | 0.8081 | 0.7371 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12333.152 | 1.0215 | 1.0587 | 0.7371 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12333.152 | 1.0155 | 1.0422 | 0.7371 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12333.152 | 0.9229 | 0.7936 | 0.7371 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12333.152 | 0.9114 | 0.7634 | 0.7371 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12333.152 | 0.1249 | -0.8811 | 0.7371 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12333.152 | 0.0241 | -0.9872 | 0.7371 | |
| MDA-MB-415 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12333.152 | 0.0235 | -0.9877 | 0.7371 | |
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12414.152 | 1.0280 | 1.0493 | 1.1325 | |
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12414.152 | 0.9210 | 0.8598 | 1.1325 | |
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12414.152 | 0.9134 | 0.8462 | 1.1325 |