Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12126.159 | 0.0158 | -0.9927 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12126.159 | 0.0151 | -0.9931 | 0.7389 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10643.14 | 1.0130 | 1.0516 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10643.14 | 1.0063 | 1.0247 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10643.14 | 1.0187 | 1.0742 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10643.14 | 1.0086 | 1.0340 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10643.14 | 1.0146 | 1.0580 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10643.14 | 0.9936 | 0.9749 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10643.14 | 0.6304 | -0.1940 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10643.14 | 0.0166 | -0.9994 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10643.14 | 0.0004 | -1.0000 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10999.152 | 1.0069 | 1.0164 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10999.152 | 1.0163 | 1.0389 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10999.152 | 0.9829 | 0.9595 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10999.152 | 0.9412 | 0.8612 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10999.152 | 0.9605 | 0.9067 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10999.152 | 1.0005 | 1.0012 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10999.152 | 0.8523 | 0.6544 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10999.152 | 0.0092 | -0.9923 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10999.152 | 0.0063 | -0.9951 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12379.152 | 1.0275 | 1.1050 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12379.152 | 1.0400 | 1.1538 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12379.152 | 1.0206 | 1.0783 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12379.152 | 1.0356 | 1.1365 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12379.152 | 1.0117 | 1.0444 | 0.5297 |