Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12112.145 | 0.9789 | 0.9780 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12112.145 | 0.7375 | 0.7073 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12112.145 | 0.7375 | 0.7073 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12112.145 | 0.1141 | -0.3526 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12112.145 | 0.1141 | -0.3526 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12112.145 | 0.0253 | -0.7039 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12112.145 | 0.0253 | -0.7039 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12112.145 | 0.0251 | -0.7052 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12112.145 | 0.0251 | -0.7052 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12112.145 | 0.0259 | -0.7006 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12112.145 | 0.0259 | -0.7006 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14203.189 | 0.9331 | 0.9200 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14203.189 | 0.9331 | 0.9200 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14203.189 | 0.9139 | 0.8965 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14203.189 | 0.9139 | 0.8965 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14203.189 | 0.9293 | 0.9153 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14203.189 | 0.9293 | 0.9153 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14203.189 | 0.9544 | 0.9457 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14203.189 | 0.9544 | 0.9457 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14203.189 | 0.9248 | 0.9099 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14203.189 | 0.9248 | 0.9099 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14203.189 | 0.3988 | 0.1629 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14203.189 | 0.3988 | 0.1629 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14203.189 | 0.0206 | -0.7976 | 1.6955 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14203.189 | 0.0206 | -0.7976 | 1.6955 |