Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12566.17 | 0.1567 | -0.4356 | 1.4648 | |
| 184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12566.17 | 0.0733 | -0.6641 | 1.4648 | |
| 184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12566.17 | 0.0733 | -0.6641 | 1.4648 | |
| 184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12566.17 | 0.0797 | -0.6444 | 1.4648 | |
| 184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12566.17 | 0.0797 | -0.6444 | 1.4648 | |
| 184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12566.17 | 0.2242 | -0.2793 | 1.4648 | |
| 184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12566.17 | 0.2242 | -0.2793 | 1.4648 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14191.189 | 0.9714 | 0.9806 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14191.189 | 0.9714 | 0.9806 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14191.189 | 0.9867 | 0.9910 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14191.189 | 0.9867 | 0.9910 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14191.189 | 0.9777 | 0.9849 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14191.189 | 0.9777 | 0.9849 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14191.189 | 0.9788 | 0.9856 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14191.189 | 0.9788 | 0.9856 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14191.189 | 0.5494 | 0.6348 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14191.189 | 0.5494 | 0.6348 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14191.189 | 0.0635 | -0.2093 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14191.189 | 0.0635 | -0.2093 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14191.189 | 0.0046 | -0.6729 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14191.189 | 0.0046 | -0.6729 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14191.189 | 0.0884 | -0.1161 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14191.189 | 0.0884 | -0.1161 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14191.189 | 1.1255 | 1.0812 | 2.9704 | |
| 21MT-1 | HER2amp | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14191.189 | 1.1255 | 1.0812 | 2.9704 |