Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12509.17 | 1.0198 | 1.0283 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12509.17 | 1.0198 | 1.0283 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12509.17 | 0.5438 | 0.2925 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12509.17 | 0.5438 | 0.2925 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12509.17 | 0.3961 | 0.0299 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12509.17 | 0.3961 | 0.0299 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12509.17 | 0.1760 | -0.4241 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12509.17 | 0.1760 | -0.4241 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12509.17 | 0.0354 | -0.8176 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12509.17 | 0.0354 | -0.8176 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12509.17 | 0.0379 | -0.8085 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12509.17 | 0.0379 | -0.8085 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12509.17 | 0.2094 | -0.3476 | 1.3955 | |
184A1 | NM | Basal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12509.17 | 0.2094 | -0.3476 | 1.3955 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12566.17 | 1.0051 | 1.0069 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12566.17 | 1.0051 | 1.0069 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12566.17 | 0.9407 | 0.9182 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12566.17 | 0.9407 | 0.9182 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12566.17 | 0.9924 | 0.9896 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12566.17 | 0.9924 | 0.9896 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12566.17 | 0.5454 | 0.3221 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12566.17 | 0.5454 | 0.3221 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12566.17 | 0.2916 | -0.1378 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12566.17 | 0.2916 | -0.1378 | 1.4648 | |
184B5 | NM | Basal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12566.17 | 0.1567 | -0.4356 | 1.4648 |