Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7533.095 | 0.7636 | 0.5209 | 0.9850 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7533.095 | 0.5589 | 0.1080 | 0.9850 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7533.095 | 0.5344 | 0.0587 | 0.9850 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7533.095 | 0.5548 | 0.0998 | 0.9850 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7533.095 | 0.3798 | -0.2516 | 0.9850 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7533.095 | 0.0079 | -0.9854 | 0.9850 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7534.095 | 0.9769 | 0.9429 | 0.8052 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7534.095 | 0.8089 | 0.5368 | 0.8052 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7534.095 | 0.6980 | 0.2796 | 0.8052 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7534.095 | 0.6525 | 0.1768 | 0.8052 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7534.095 | 0.6151 | 0.0938 | 0.8052 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7534.095 | 0.6344 | 0.1365 | 0.8052 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7534.095 | 0.6893 | 0.2600 | 0.8052 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7534.095 | 0.0299 | -0.9744 | 0.8052 | |
| SUM225CWN | HER2amp | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7534.095 | 0.0005 | -0.9999 | 0.8052 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7535.095 | 1.0374 | 1.0924 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7535.095 | 0.9014 | 0.7604 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7535.095 | 0.9679 | 0.9212 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7535.095 | 0.7108 | 0.3144 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7535.095 | 0.3756 | -0.4002 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7535.095 | 0.2799 | -0.5823 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7535.095 | 0.2781 | -0.5856 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7535.095 | 0.0125 | -0.9909 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7535.095 | 0.0041 | -0.9977 | 0.8131 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7537.095 | 0.9809 | 0.9806 | 1.9867 |