Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7470.095 | 0.1923 | -0.4999 | 1.1893 | |
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7470.095 | 0.2942 | -0.2852 | 1.1893 | |
| HCC70 | TNBC | Basal A | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7470.095 | 0.0058 | -0.9738 | 1.1893 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7471.095 | 1.0190 | 1.0164 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7471.095 | 0.8769 | 0.8893 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7471.095 | 0.4842 | 0.4605 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7471.095 | 0.1843 | -0.0393 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7471.095 | 0.1294 | -0.1758 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7471.095 | 0.0999 | -0.2631 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7471.095 | 0.1280 | -0.1796 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7471.095 | 0.1579 | -0.1016 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7471.095 | 0.0022 | -0.8602 | 2.3069 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7472.095 | 1.0661 | 1.0511 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7472.095 | 0.9756 | 0.9806 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7472.095 | 0.7772 | 0.8107 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7472.095 | 0.4873 | 0.5063 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7472.095 | 0.2773 | 0.2060 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7472.095 | 0.1750 | 0.0057 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7472.095 | 0.2037 | 0.0677 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7472.095 | 0.2645 | 0.1837 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7472.095 | 0.0011 | -0.8636 | 2.5356 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7473.095 | 1.1528 | 1.0926 | 3.1412 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7473.095 | 0.9003 | 0.9342 | 3.1412 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7473.095 | 0.3264 | 0.4003 | 3.1412 | |
| Hs 578T | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7473.095 | 0.1110 | -0.0068 | 3.1412 |