Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 10580.143 | 0.9390 | 0.8556 | 0.8402 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 10580.143 | 0.4097 | -0.3086 | 0.8402 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 10580.143 | 0.2445 | -0.6259 | 0.8402 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10754.143 | 1.0033 | 1.0055 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10754.143 | 0.9201 | 0.8666 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 10754.143 | 1.0245 | 1.0404 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 10754.143 | 0.8876 | 0.8119 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 10754.143 | 0.9487 | 0.9147 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 10754.143 | 0.9774 | 0.9625 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 10754.143 | 0.9036 | 0.8389 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 10754.143 | 0.3473 | -0.1672 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 10754.143 | 0.2819 | -0.2993 | 1.2072 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 11938.143 | 0.9523 | 0.8225 | 0.5258 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 11938.143 | 0.9910 | 0.9658 | 0.5258 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 11938.143 | 1.0240 | 1.0923 | 0.5258 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 11938.143 | 1.0185 | 1.0710 | 0.5258 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 11938.143 | 1.0223 | 1.0858 | 0.5258 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 11938.143 | 1.1036 | 1.4124 | 0.5258 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 11938.143 | 1.0580 | 1.2265 | 0.5258 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 11938.143 | 0.5422 | -0.3758 | 0.5258 | ||
| UACC-812 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 11938.143 | 0.4586 | -0.5460 | 0.5258 | ||
| ZR-75-1 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 11660.143 | 0.9801 | 0.9617 | 1.0389 | ||
| ZR-75-1 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 11660.143 | 0.9676 | 0.9375 | 1.0389 | ||
| ZR-75-1 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 11660.143 | 0.9848 | 0.9708 | 1.0389 | ||
| ZR-75-1 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 11660.143 | 1.0126 | 1.0242 | 1.0389 |