Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 12084.143 | 0.8253 | 0.7348 | 1.3499 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 12084.143 | 1.0067 | 1.0099 | 1.3499 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 12084.143 | 0.9288 | 0.8935 | 1.3499 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 12084.143 | 0.8698 | 0.8036 | 1.3499 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 12084.143 | 0.6711 | 0.4884 | 1.3499 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 12084.143 | 0.5687 | 0.3166 | 1.3499 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 12084.143 | 0.4419 | 0.0921 | 1.3499 | ||
| HCC1395 | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 12084.143 | 0.3823 | -0.0190 | 1.3499 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12001.143 | 0.9822 | 0.9426 | 0.6160 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12001.143 | 0.9918 | 0.9734 | 0.6160 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 12001.143 | 1.0229 | 1.0749 | 0.6160 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 12001.143 | 0.9764 | 0.9238 | 0.6160 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 12001.143 | 0.8734 | 0.6055 | 0.6160 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 12001.143 | 0.7908 | 0.3663 | 0.6160 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 12001.143 | 0.6221 | -0.0745 | 0.6160 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 12001.143 | 0.4714 | -0.4100 | 0.6160 | ||
| HCC1419 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 12001.143 | 0.4612 | -0.4306 | 0.6160 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10693.143 | 1.0074 | 1.0197 | 0.7509 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10693.143 | 0.9908 | 0.9756 | 0.7509 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10693.143 | 0.9955 | 0.9881 | 0.7509 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10693.143 | 1.0352 | 1.0942 | 0.7509 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10693.143 | 0.9939 | 0.9838 | 0.7509 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10693.143 | 1.0036 | 1.0096 | 0.7509 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10693.143 | 0.9411 | 0.8448 | 0.7509 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10693.143 | 0.5933 | -0.0021 | 0.7509 |