Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7463.07 | 0.3122 | -0.7268 | 0.5848 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7463.09 | 0.9670 | 0.8813 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7463.09 | 0.9379 | 0.7794 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7463.09 | 1.0255 | 1.0939 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7463.09 | 0.9518 | 0.8276 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7463.09 | 0.9986 | 0.9949 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7463.09 | 0.9280 | 0.7452 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7463.09 | 0.7805 | 0.2728 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7463.09 | 0.8575 | 0.5111 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7463.09 | 0.7362 | 0.1441 | 0.5483 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7463.098 | 0.9733 | 0.8923 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7463.098 | 0.9658 | 0.8624 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7463.098 | 0.9888 | 0.9544 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7463.098 | 0.9549 | 0.8197 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7463.098 | 1.0194 | 1.0805 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7463.098 | 0.9871 | 0.9477 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7463.098 | 0.8274 | 0.3564 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7463.098 | 0.4641 | -0.5852 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7463.098 | 0.3259 | -0.7990 | 0.4880 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7464.071 | 1.0403 | 1.1459 | 0.5610 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7464.071 | 1.0054 | 1.0193 | 0.5610 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7464.071 | 0.9806 | 0.9312 | 0.5610 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7464.071 | 0.9984 | 0.9942 | 0.5610 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7464.071 | 1.0117 | 1.0418 | 0.5610 | |
| HCC2185 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7464.071 | 0.9956 | 0.9845 | 0.5610 |