Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 5908.071 | 0.9446 | 0.8375 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 5908.071 | 0.9547 | 0.8669 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 5908.071 | 0.9560 | 0.8705 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 5908.071 | 0.9557 | 0.8698 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 5908.071 | 0.8855 | 0.6694 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 5908.071 | 0.8351 | 0.5302 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 5908.071 | 0.7482 | 0.2995 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 5908.071 | 0.0185 | -0.9947 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 5908.071 | 0.0148 | -0.9962 | 0.6729 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5908.091 | 0.9647 | 0.8640 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5908.091 | 0.9037 | 0.6404 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5908.091 | 0.9502 | 0.8098 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5908.091 | 0.9416 | 0.7777 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5908.091 | 0.9123 | 0.6712 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5908.091 | 0.8059 | 0.3109 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5908.091 | 0.7584 | 0.1639 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5908.091 | 0.0161 | -0.9994 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 5908.091 | 0.0160 | -0.9994 | 0.5109 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5908.098 | 0.9745 | 0.9170 | 0.6091 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5908.098 | 0.9465 | 0.8272 | 0.6091 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5908.098 | 0.9359 | 0.7938 | 0.6091 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5908.098 | 0.9054 | 0.6990 | 0.6091 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5908.098 | 0.9619 | 0.8764 | 0.6091 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5908.098 | 0.8754 | 0.6073 | 0.6091 | |
| BT-483 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5908.098 | 0.8145 | 0.4280 | 0.6091 |