Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 7849.001 | 0.8478 | 0.4654 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 7849.001 | 0.6476 | -0.1179 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 7849.001 | 0.4142 | -0.6199 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9420.001 | 0.9811 | 0.8887 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9420.001 | 0.9561 | 0.7478 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9420.001 | 1.0178 | 1.1087 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9420.001 | 0.8720 | 0.3257 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9420.001 | 0.9030 | 0.4727 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9420.001 | 0.8278 | 0.1345 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9420.001 | 0.8651 | 0.2945 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9420.001 | 0.6811 | -0.3683 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9420.001 | 0.4093 | -0.8630 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10263.001 | 1.0797 | 1.5309 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 10263.001 | 0.9047 | 0.4707 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 10263.001 | 1.0098 | 1.0610 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 10263.001 | 0.9326 | 0.6145 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 10263.001 | 0.9259 | 0.5791 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 10263.001 | 0.9097 | 0.4959 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 10263.001 | 0.8870 | 0.3841 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 10263.001 | 0.7391 | -0.2093 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 10263.001 | 0.6468 | -0.4750 | 0.3258 | |
| HCC3153 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7853.001 | 0.9674 | 0.9584 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7853.001 | 0.9550 | 0.9425 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7853.001 | 0.9935 | 0.9917 | 1.5775 | |
| HCC3153 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7853.001 | 0.9517 | 0.9382 | 1.5775 |