Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 9376.001 | 0.8793 | 0.8644 | 1.8315 | |
| HCC1806 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 9376.001 | 0.9854 | 0.9840 | 1.8315 | |
| HCC1806 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 9376.001 | 0.7070 | 0.6550 | 1.8315 | |
| HCC1806 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 9376.001 | 0.0452 | -0.6314 | 1.8315 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7833.001 | 0.9833 | 0.9681 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7833.001 | 0.7773 | 0.5721 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7833.001 | 0.6885 | 0.4003 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7833.001 | 0.8137 | 0.6424 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7833.001 | 0.6225 | 0.2717 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7833.001 | 0.6081 | 0.2435 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7833.001 | 0.5583 | 0.1461 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7833.001 | 0.5983 | 0.2244 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7833.001 | 0.1215 | -0.7330 | 1.0468 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7834.001 | 0.9989 | 0.9989 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7834.001 | 0.9914 | 0.9914 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7834.001 | 0.9794 | 0.9796 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7834.001 | 0.9223 | 0.9216 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7834.001 | 0.8064 | 0.7981 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7834.001 | 0.7480 | 0.7325 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7834.001 | 0.7806 | 0.7694 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7834.001 | 0.6140 | 0.5713 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7834.001 | 0.0910 | -0.3887 | 2.0219 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10262.001 | 1.0057 | 1.0187 | 0.6105 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 10262.001 | 0.9968 | 0.9894 | 0.6105 | |
| HCC1937 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 10262.001 | 1.0053 | 1.0173 | 0.6105 |