Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 9233.001 | 0.0942 | -0.8187 | 0.9839 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7811.001 | 1.0319 | 1.1458 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7811.001 | 0.9582 | 0.8175 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7811.001 | 1.0104 | 1.0468 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7811.001 | 0.9098 | 0.6184 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7811.001 | 0.2741 | -0.8898 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7811.001 | 0.2664 | -0.8967 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7811.001 | 0.4492 | -0.6669 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7811.001 | 0.2929 | -0.8722 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7811.001 | 0.1789 | -0.9576 | 0.4464 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7812.001 | 1.0890 | 1.1768 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7812.001 | 1.0501 | 1.0997 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7812.001 | 1.0697 | 1.1386 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7812.001 | 0.8307 | 0.6633 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7812.001 | 0.1820 | -0.6323 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7812.001 | 0.1874 | -0.6214 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7812.001 | 0.2654 | -0.4650 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7812.001 | 0.1753 | -0.6457 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7812.001 | 0.0723 | -0.8531 | 1.0060 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9244.001 | 1.2070 | 1.8300 | 0.5421 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 9244.001 | 0.9971 | 0.9893 | 0.5421 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 9244.001 | 1.0697 | 1.2647 | 0.5421 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 9244.001 | 0.7104 | 0.0643 | 0.5421 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 9244.001 | 0.2062 | -0.8914 | 0.5421 | |
| HCC1187 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 9244.001 | 0.2141 | -0.8836 | 0.5421 |