Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10753.15 | 0.9189 | 0.8838 | 1.4129 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10753.15 | 0.4669 | 0.1665 | 1.4129 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10753.15 | 0.3050 | -0.1370 | 1.4129 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10753.15 | 0.1791 | -0.4079 | 1.4129 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12000.169 | 0.9579 | 0.9021 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12000.169 | 0.9726 | 0.9362 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12000.169 | 0.9645 | 0.9174 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12000.169 | 0.9574 | 0.9009 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12000.169 | 0.9553 | 0.8960 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12000.169 | 0.9121 | 0.7962 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12000.169 | 0.8122 | 0.5687 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12000.169 | 0.7310 | 0.3871 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12000.169 | 0.5492 | -0.0066 | 0.8565 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12084.16 | 1.0124 | 1.0222 | 1.1178 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12084.16 | 0.9628 | 0.9332 | 1.1178 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12084.16 | 0.9863 | 0.9754 | 1.1178 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12084.16 | 1.1000 | 1.1780 | 1.1178 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12084.16 | 1.0007 | 1.0012 | 1.1178 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12084.16 | 1.0516 | 1.0921 | 1.1178 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12084.16 | 0.8360 | 0.7038 | 1.1178 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12084.16 | 0.7353 | 0.5190 | 1.1178 | ||
| HCC1395 | TNBC | Basal B | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12084.16 | 0.4543 | -0.0127 | 1.1178 | ||
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12001.169 | 0.9883 | 0.9675 | 0.7194 | ||
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12001.169 | 1.0004 | 1.0011 | 0.7194 | ||
| HCC1419 | HER2amp | Luminal | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12001.169 | 0.9515 | 0.8665 | 0.7194 |