Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7849.011 | 0.7326 | 0.1320 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7849.011 | 0.7965 | 0.3190 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7849.011 | 0.7533 | 0.1912 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7849.011 | 0.6887 | 0.0109 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7849.011 | 0.6562 | -0.0746 | 0.5467 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7853.011 | 1.1246 | 1.1492 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7853.011 | 0.9415 | 0.9276 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7853.011 | 0.9732 | 0.9670 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7853.011 | 0.6761 | 0.5737 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7853.011 | 0.6385 | 0.5195 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7853.011 | 0.7057 | 0.6156 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7853.011 | 0.6628 | 0.5548 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7853.011 | 0.6533 | 0.5410 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7853.011 | 0.6335 | 0.5123 | 1.6331 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9028.075 | 1.0028 | 1.0092 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00924 | uM | 9028.075 | 0.2621 | -0.7845 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9028.075 | 0.1729 | -0.8921 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9028.075 | 0.1318 | -0.9313 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9028.075 | 0.1263 | -0.9361 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9028.075 | 0.1323 | -0.9309 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9028.075 | 0.1115 | -0.9480 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9028.075 | 0.1117 | -0.9479 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 722 | uM | 9028.075 | 0.0986 | -0.9576 | 0.6011 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9453.011 | 1.4791 | 2.3093 | 0.7773 | |
| HCC38 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9453.011 | 1.4551 | 2.2405 | 0.7773 |