Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9797.012 | 0.4731 | -0.5806 | 0.4792 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9797.012 | 0.5176 | -0.4941 | 0.4792 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9797.012 | 0.4816 | -0.5647 | 0.4792 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9797.012 | 0.5195 | -0.4901 | 0.4792 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10139.012 | 1.0258 | 1.0605 | 0.8556 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10139.012 | 1.0052 | 1.0121 | 0.8556 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10139.012 | 1.0114 | 1.0267 | 0.8556 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10139.012 | 0.8761 | 0.7135 | 0.8556 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10139.012 | 0.6201 | 0.1440 | 0.8556 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10139.012 | 0.4499 | -0.2138 | 0.8556 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10139.012 | 0.4366 | -0.2408 | 0.8556 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10139.012 | 0.4867 | -0.1379 | 0.8556 | |
| SUM1315MO2 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10139.012 | 0.4878 | -0.1358 | 0.8556 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9830.012 | 0.9774 | 0.9753 | 1.8343 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9830.012 | 1.0765 | 1.0820 | 1.8343 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9830.012 | 0.5250 | 0.4076 | 1.8343 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9830.012 | 0.0898 | -0.4623 | 1.8343 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9830.012 | 0.0534 | -0.5949 | 1.8343 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9830.012 | 0.0479 | -0.6185 | 1.8343 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9830.012 | 0.0542 | -0.5918 | 1.8343 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9830.012 | 0.0483 | -0.6166 | 1.8343 | |
| SUM149PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9830.012 | 0.0513 | -0.6038 | 1.8343 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7918.012 | 0.9659 | 0.9768 | 2.9753 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7918.012 | 1.0363 | 1.0241 | 2.9753 | |
| SUM159PT | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7918.012 | 0.4706 | 0.5524 | 2.9753 |