Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9157.012 | 1.0226 | 1.0525 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9157.012 | 1.0435 | 1.1010 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9157.012 | 0.9662 | 0.9219 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9157.012 | 0.3992 | -0.3089 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9157.012 | 0.3861 | -0.3352 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9157.012 | 0.3610 | -0.3850 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9157.012 | 0.3357 | -0.4345 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9157.012 | 0.3161 | -0.4725 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9157.012 | 0.2685 | -0.5634 | 0.8641 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9158.049 | 1.1295 | 1.6952 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9158.049 | 1.0736 | 1.3800 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9158.049 | 0.9382 | 0.7108 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9158.049 | 0.3860 | -0.8058 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9158.049 | 0.3911 | -0.7995 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9158.049 | 0.4047 | -0.7820 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9158.049 | 0.6933 | -0.1849 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9158.049 | 0.3577 | -0.8389 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9158.049 | 0.5676 | -0.5006 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9163.024 | 1.0298 | 1.1094 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9163.024 | 1.0300 | 1.1100 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9163.024 | 1.0141 | 1.0512 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9163.024 | 0.3334 | -0.7262 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9163.024 | 0.3107 | -0.7590 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9163.024 | 0.3055 | -0.7662 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9163.024 | 0.2738 | -0.8083 | 0.5524 |