Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 6.67 | uM | 7488.016 | 0.2697 | -0.3144 | 1.2238 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 33.3 | uM | 7488.016 | 0.1546 | -0.5650 | 1.2238 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7871.016 | 1.0631 | 1.1227 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7871.016 | 1.0440 | 1.0856 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7871.016 | 1.0270 | 1.0525 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7871.016 | 1.0786 | 1.1529 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7871.016 | 1.0384 | 1.0747 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.267 | uM | 7871.016 | 0.9683 | 0.9383 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 1.33 | uM | 7871.016 | 0.4953 | 0.0091 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 6.67 | uM | 7871.016 | 0.4362 | -0.1082 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 33.3 | uM | 7871.016 | 0.3392 | -0.3020 | 1.0272 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7872.016 | 0.9388 | 0.9167 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7872.016 | 0.9633 | 0.9502 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7872.016 | 1.0101 | 1.0135 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7872.016 | 0.9851 | 0.9799 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7872.016 | 0.9785 | 0.9709 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.267 | uM | 7872.016 | 0.9012 | 0.8645 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 1.33 | uM | 7872.016 | 0.4029 | 0.0836 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 6.67 | uM | 7872.016 | 0.3988 | 0.0761 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 33.3 | uM | 7872.016 | 0.0786 | -0.6400 | 1.4834 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9566.132 | 1.0183 | 1.0152 | 2.4013 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9566.132 | 0.9273 | 0.9381 | 2.4013 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9566.132 | 0.8793 | 0.8957 | 2.4013 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9566.132 | 0.9716 | 0.9761 | 2.4013 | |
| MCF 10F | NM | - | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9566.132 | 0.8559 | 0.8745 | 2.4013 |