Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7811.044 | 1.0582 | 1.4042 | 0.3073 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7811.044 | 1.0515 | 1.3554 | 0.3073 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7811.044 | 1.0840 | 1.6000 | 0.3073 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7811.044 | 1.0727 | 1.5130 | 0.3073 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7811.044 | 0.7641 | -0.1669 | 0.3073 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7812.016 | 0.9738 | 0.9507 | 1.0628 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7812.016 | 1.0692 | 1.1300 | 1.0628 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7812.016 | 0.9628 | 0.9300 | 1.0628 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7812.016 | 0.9832 | 0.9684 | 1.0628 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7812.016 | 0.9817 | 0.9655 | 1.0628 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.267 | uM | 7812.016 | 1.0437 | 1.0821 | 1.0628 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 1.33 | uM | 7812.016 | 0.9757 | 0.9542 | 1.0628 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 6.67 | uM | 7812.016 | 0.9881 | 0.9775 | 1.0628 | |
| HCC1187 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 33.3 | uM | 7812.016 | 0.6895 | 0.4096 | 1.0628 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7813.016 | 1.0904 | 1.2136 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7813.016 | 0.9082 | 0.7866 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7813.016 | 1.0489 | 1.1151 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7813.016 | 1.1601 | 1.3802 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7813.016 | 1.0670 | 1.1579 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7813.016 | 1.0804 | 1.1897 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7813.016 | 1.0502 | 1.1183 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7813.016 | 0.7803 | 0.4954 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7813.016 | 0.1541 | -0.7767 | 0.8531 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7814.016 | 0.9957 | 0.9901 | 0.8623 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7814.016 | 0.9951 | 0.9887 | 0.8623 |