Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 5896.084 | 1.0003 | 1.0004 | 1.5200 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 5896.084 | 0.9854 | 0.9808 | 1.5200 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 5896.084 | 1.0138 | 1.0181 | 1.5200 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 5896.084 | 0.5514 | 0.3519 | 1.5200 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 5896.084 | 0.0182 | -0.8565 | 1.5200 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 5896.084 | 0.0081 | -0.9161 | 1.5200 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 5896.084 | 0.0084 | -0.9138 | 1.5200 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 5897.085 | 0.9934 | 0.9893 | 1.2392 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 5897.085 | 1.0016 | 1.0026 | 1.2392 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 5897.085 | 0.9857 | 0.9768 | 1.2392 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 5897.085 | 0.9844 | 0.9748 | 1.2392 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 5897.085 | 0.9301 | 0.8865 | 1.2392 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 5897.085 | 0.8050 | 0.6789 | 1.2392 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 5897.085 | 0.0413 | -0.8473 | 1.2392 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 5897.085 | 0.0066 | -0.9650 | 1.2392 | |
| 184B5 | NM | Basal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 5897.085 | 0.0070 | -0.9636 | 1.2392 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 5898.085 | 0.9391 | 0.8294 | 0.7048 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 5898.085 | 0.9004 | 0.7233 | 0.7048 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 5898.085 | 0.9649 | 0.9010 | 0.7048 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 5898.085 | 0.9812 | 0.9470 | 0.7048 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 5898.085 | 0.9455 | 0.8472 | 0.7048 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 5898.085 | 0.8151 | 0.4965 | 0.7048 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 5898.085 | 0.0080 | -0.9979 | 0.7048 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 5898.085 | 0.0128 | -0.9959 | 0.7048 | |
| 600MPE | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 5898.085 | 0.0077 | -0.9980 | 0.7048 |