Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Everolimus | MTOR | MTOR | 66.7 | uM | 11058.156 | 0.0095 | -0.8063 | 1.9927 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 11852.156 | 1.1670 | 1.3300 | 1.0109 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 11852.156 | 0.9599 | 0.9206 | 1.0109 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 11852.156 | 0.6837 | 0.3730 | 1.0109 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 11852.156 | 0.6173 | 0.2410 | 1.0109 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 11852.156 | 0.5569 | 0.1209 | 1.0109 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 11852.156 | 0.5471 | 0.1013 | 1.0109 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 11852.156 | 0.5756 | 0.1582 | 1.0109 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 11852.156 | 0.4735 | -0.0453 | 1.0109 | |
| SUM52PE | HR+ | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 11852.156 | 0.0126 | -0.9736 | 1.0109 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 10939.156 | 1.0173 | 1.0209 | 1.6506 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 10939.156 | 1.0327 | 1.0394 | 1.6506 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 10939.156 | 1.0000 | 1.0000 | 1.6506 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 10939.156 | 0.8383 | 0.7973 | 1.6506 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 10939.156 | 0.6648 | 0.5617 | 1.6506 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 10939.156 | 0.6890 | 0.5959 | 1.6506 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 10939.156 | 0.6574 | 0.5512 | 1.6506 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 10939.156 | 0.6091 | 0.4811 | 1.6506 | |
| T47D | HR+ | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 10939.156 | 0.0182 | -0.8232 | 1.6506 | |
| T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.000171 | uM | 12608.164 | 0.9756 | 0.9557 | 1.1044 | |
| T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.000853 | uM | 12608.164 | 0.9433 | 0.8971 | 1.1044 | |
| T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.00427 | uM | 12608.164 | 0.9542 | 0.9169 | 1.1044 | |
| T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.0213 | uM | 12608.164 | 0.9158 | 0.8469 | 1.1044 | |
| T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.107 | uM | 12608.164 | 0.8196 | 0.6702 | 1.1044 | |
| T47DKBLUC | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.533 | uM | 12608.164 | 0.8223 | 0.6752 | 1.1044 |