Buparlisib KINOMEscan - Dataset (ID:20262)

Proteins Studied

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200318 CDK14 200318 O94921
Cyclin-dependent kinase 14; serine/threonine-protein kinase PFTAIRE-1; PFTK1
KINOMEscan Wild Type; Full length
200361 KPCD3 200361 O94806
Protein kinase D3; EPK2; nPKC-NU; PKC-NU; PKD3; PRKCN; PRKD3
KINOMEscan Wild Type; Partial length
200228 LOK 200228 O94804
Serine/threonine-protein kinase 10
KINOMEscan Wild Type; Partial length
200118 DRAK2 200118 O94768
Serine/threonine kinase 17b; DRAK2; STK17B
KINOMEscan Wild Type; Full length
200086 CDKL5 200086 O76039
Cyclin-dependent kinase-like 5; CDKL5; ISSX; STK9
KINOMEscan Wild Type; Partial length
200304 PAK3 200304 O75914
P21 protein (Cdc42/Rac)-activated kinase 3; bPAK; CDKN1A; hPAK3; MRX30; MRX47; OPHN3; PAK3; PAK3beta
KINOMEscan Wild Type; Full length
200322 PIK3C2G 200322 O75747
Phosphoinositide-3-kinase, class 2, gamma polypeptide; MGC163149; PI3K-C2GAMMA; PIK3C2G
KINOMEscan Wild Type; Partial length
200420 STK16 200420 O75716
Serine/threonine kinase 16; FLJ39635; KRCT; MGC16211; MPSK; MPSK1; PKL12; STK16; TSF1
KINOMEscan Wild Type; Partial length
200390 RPS6KA4(Kin.Dom.1-N-terminal) 200390 O75676
Ribosomal protein S6 kinase, 90kDa, polypeptide 4; MSK2; RPS6KA4; RSK-B
KINOMEscan Kin.Dom.1-N-terminal Wild Type; Partial length
200392 RPS6KA4(Kin.Dom.2-C-terminal) 200392 O75676
Ribosomal protein S6 kinase, 90kDa, polypeptide 4; MSK2; MSK2~b; RPS6KA4; RSK-B
KINOMEscan Kin.Dom.2-C-terminal Wild Type; Partial length
200396 RPS6KA5(Kin.Dom.2-C-terminal) 200396 O75582
Ribosomal protein S6 kinase, 90kDa, polypeptide 5; MGC1911; MSK1; MSK1~b; MSPK1; RLPK; RPS6KA5
KINOMEscan Kin.Dom.2-C-terminal Wild Type; Partial length
200394 RPS6KA5(Kin.Dom.1-N-terminal) 200394 O75582
Ribosomal protein S6 kinase, 90kDa, polypeptide 5; MGC1911; MSK1; MSPK1; RLPK; RPS6KA5
KINOMEscan Kin.Dom.1-N-terminal Wild Type; Partial length
200157 ERN1 200157 O75460
Endoplasmic reticulum to nucleus signaling 1; ERN1; FLJ30999; hIRE1p; IRE1; IRE1a; IRE1P; MGC163277; MGC163279
KINOMEscan Wild Type; Partial length
200455 ULK1 200455 O75385
Serine/threonine-protein kinase ULK1; Unc-51-like kinase 1 (C. elegans); ATG1; FLJ38455; FLJ46475; ULK1; UNC51; Unc51.1
KINOMEscan Wild Type; Partial length
200382 ROCK2 200382 O75116
Rho-associated protein kinase 2; Rho-associated, coiled-coil containing protein kinase 2; KIAA0619; ROCK2
KINOMEscan Wild Type; Partial length
200207 JAK2(JH1domain-catalytic) 200207 O60674
Janus kinase 2; JAK2; JAK2-catalytic; JTK10
KINOMEscan JH1domain-catalytic Wild Type; Partial length
200341 PIP5K1C 200341 O60331
Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; KIAA0589; LCCS3; PIP5K1C; PIP5Kgamma; PIP5K-GAMMA; PIPKIg_v4
KINOMEscan Wild Type; Partial length
200041 NUAK1 200041 O60285
NUAK family, SNF1-like kinase, 1; ARK5; KIAA0537; NUAK1
KINOMEscan Wild Type; Partial length
200378 RIPK2 200378 O43353
Receptor-interacting serine/threonine-protein kinase 2; CARD3; CARDIAK; CCK; GIG30; RICK; RIP2; RIPK2
KINOMEscan Wild Type; Partial length
200426 TAK1 200426 O43318
Mitogen-activated protein kinase kinase kinase 7; MAP3K7; MEKK7; TAK1; TGF1a
KINOMEscan Wild Type; Partial length
200108 DAPK3 200108 O43293
Death-associated protein kinase 3; DAPK3; FLJ36473; ZIP; ZIPK
KINOMEscan Wild Type; Partial length
200233 M3K13 200233 O43283
Mitogen-activated protein kinase kinase kinase 13; LZK; MAP3K13; MEKK13; MGC133196
KINOMEscan Wild Type; Full length
200314 PDPK1 200314 O15530
3-phosphoinositide dependent protein kinase-1; MGC20087; MGC35290; PDK1; PDPK1; PRO0461
KINOMEscan Wild Type; Full length
200300 MK13 200300 O15264
Mitogen-activated protein kinase 13; MAPK13; MGC99536; p38d; p38delta; p38-delta; PRKM13; SAPK4
KINOMEscan Wild Type; Full length
200147 EPHB6 200147 O15197
EPH receptor B6; EPHB6; HEP; MGC129910; MGC129911
KINOMEscan Wild Type; Partial length