Buparlisib KINOMEscan - Dataset (ID:20262)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200333 | PIK3CB | 200333 | P42338 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; DKFZp779K1237; MGC133043; P110BETA; PI3K; PI3KBETA; PIK3C1; PIK3CB; PI3K-beta | KINOMEscan | Wild Type; Partial length | |||
| 200325 | PIK3CA(E542K) | 200325 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E542K | Mutation (E542K); Partial length | ||
| 200323 | PIK3CA | 200323 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | Wild Type; Partial length | |||
| 200324 | PIK3CA(C420R) | 200324 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | C420R | Mutation (C420R); Partial length | ||
| 200326 | PIK3CA(E545A) | 200326 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545A | Mutation (E545A); Partial length | ||
| 200327 | PIK3CA(E545K) | 200327 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545K | Mutation (E545K); Partial length | ||
| 200328 | PIK3CA(H1047L) | 200328 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047L | Mutation (H1047L); Partial length | ||
| 200329 | PIK3CA(H1047Y) | 200329 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047Y | Mutation (H1047Y); Partial length | ||
| 200330 | PIK3CA(I800L) | 200330 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | I800L | Mutation (I800L); Partial length | ||
| 200331 | PIK3CA(M1043I) | 200331 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | M1043I | Mutation (M1043I); Partial length | ||
| 200332 | PIK3CA(Q546K) | 200332 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | Q546K | Mutation (Q546K); Partial length | ||
| 200357 | KPCI | 200357 | P41743 | Protein kinase C, iota; DXS1179E; MGC26534; nPKC-iota; PKCI; PRKCI | KINOMEscan | Wild Type; Partial length | |||
| 200095 | CSK | 200095 | P41240 | C-src tyrosine kinase; CSK; MGC117393 | KINOMEscan | Wild Type; Full length | |||
| 200434 | TGFBR2 | 200434 | P37173 | Transforming growth factor, beta receptor II (70/80kDa); AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TGFbeta-RII; TGFBR2; TGFR-2 | KINOMEscan | Wild Type; Partial length | |||
| 200031 | ACVRL1 | 200031 | P37023 | Activin A receptor type II-like 1; ACVRL1; ACVRLK1; ALK1; ALK-1; HHT; HHT2; ORW2; SKR3; TSR-I | KINOMEscan | Wild Type; Partial length | |||
| 200433 | TGFBR1 | 200433 | P36897 | Transforming growth factor, beta receptor 1; AAT5; ACVRLK4; ALK5; ALK-5; LDS1A; LDS2A; SKR4; TGFBR1; TGFR-1 | KINOMEscan | Wild Type; Partial length | |||
| 200028 | ACVR1B | 200028 | P36896 | Activin A receptor, type IB; ACTRIB; ACVR1B; ACVRLK4; ALK4; SKR2 | KINOMEscan | Wild Type; Partial length | |||
| 200050 | BMPR1A | 200050 | P36894 | Bone morphogenetic protein receptor, type IA; 10q23del; ACVRLK3; ALK3; BMPR1A; CD292; SKR5 | KINOMEscan | Wild Type; Partial length | |||
| 200168 | FLT3 | 200168 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | Wild Type; Partial length | |||
| 201327 | FLT3(ITD,F691L) | 201327 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD,F691L | |||
| 200472 | FLT3-autoinhibited | 200472 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ||||
| 201325 | FLT3(D835V) | 201325 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835V | |||
| 200174 | FLT3(R834Q) | 200174 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | R834Q | Mutation (R834Q); Partial length | ||
| 200173 | FLT3(N841I) | 200173 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | N841I | Mutation (N841I); Partial length | ||
| 200172 | FLT3(K663Q) | 200172 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | K663Q | Mutation (K663Q); Partial length |