GDC-0941 KINOMEscan-3 - Dataset (ID:20261)

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Small Molecule Protein % Control Assay compound conc Conc unit
Pictilisib DYRK2 100.0 100
nM
Pictilisib EGFR 100.0 1000
nM
Pictilisib EGFR 99.0 100
nM
Pictilisib EGFR(E746-A750del) 82.0 1000
nM
Pictilisib EGFR(E746-A750del) 91.0 100
nM
Pictilisib EGFR(G719C) 100.0 100
nM
Pictilisib EGFR(G719C) 100.0 1000
nM
Pictilisib EGFR(G719S) 93.0 1000
nM
Pictilisib EGFR(G719S) 99.0 100
nM
Pictilisib EGFR(L747-E749del, A750P) 100.0 1000
nM
Pictilisib EGFR(L747-E749del, A750P) 100.0 100
nM
Pictilisib EGFR(L747-S752del, P753S) 66.0 1000
nM
Pictilisib EGFR(L747-S752del, P753S) 64.0 100
nM
Pictilisib EGFR(L747-T751del,Sins) 89.0 100
nM
Pictilisib EGFR(L747-T751del,Sins) 98.0 1000
nM
Pictilisib EGFR(L858R) 100.0 100
nM
Pictilisib EGFR(L858R) 100.0 1000
nM
Pictilisib EGFR(L858R,T790M) 100.0 1000
nM
Pictilisib EGFR(L858R,T790M) 98.0 100
nM
Pictilisib EGFR(L861Q) 77.0 1000
nM
Pictilisib EGFR(L861Q) 88.0 100
nM
Pictilisib EGFR(S752-I759del) 91.0 100
nM
Pictilisib EGFR(S752-I759del) 94.0 1000
nM
Pictilisib EGFR(T790M) 100.0 100
nM
Pictilisib EGFR(T790M) 100.0 1000
nM