LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (drug combination treatments). Dataset 2 of 2: Mean cell count and mean normalized growth rate inhibition values across technical replicates. - Dataset (ID:20260)

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Cell Small Molecule Small Mol 1 Concentration Small Mol 1 Conc Unit Small Molecule 2 Small Mol 2 Concentration Small Mol 2 Conc Unit Biological Replicate Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Dactolisib
0.0047
uM
 Lapatinib
1.9245
uM
 2 1843 4191 5189 0.7331
BT-20 Dactolisib
0.0047
uM
 Lapatinib
3.3333
uM
 2 1843 4453 5189 0.8046
BT-20 Dactolisib
0.0047
uM
 Lapatinib
5.7735
uM
 2 1843 3871 5189 0.6427
BT-20 Dactolisib
0.0047
uM
 Lapatinib
10
uM
 2 1843 2707 5189 0.2913
BT-20 Dactolisib
0.0047
uM
 NVP-TAE684
0.3704
uM
 2 1843 4555 5189 0.8334
BT-20 Dactolisib
0.0047
uM
 NVP-TAE684
1.1111
uM
 2 1843 4057 5189 0.6953
BT-20 Dactolisib
0.0047
uM
 NVP-TAE684
3.3333
uM
 2 1843 1345 5189 -0.1922
BT-20 Dactolisib
0.0047
uM
 Neratinib
0.0713
uM
 2 1843 4125 5189 0.7134
BT-20 Dactolisib
0.0047
uM
 Neratinib
0.1235
uM
 2 1843 3990 5189 0.6759
BT-20 Dactolisib
0.0047
uM
 Neratinib
0.2138
uM
 2 1843 3601 5189 0.5645
BT-20 Dactolisib
0.0047
uM
 Neratinib
0.3704
uM
 2 1843 3151 5189 0.4309
BT-20 Dactolisib
0.0047
uM
 Neratinib
0.6415
uM
 2 1843 2899 5189 0.3524
BT-20 Dactolisib
0.0047
uM
 Neratinib
1.1111
uM
 2 1843 2493 5189 0.2227
BT-20 Dactolisib
0.0047
uM
 Neratinib
1.9245
uM
 2 1843 2674 5189 0.2829
BT-20 Dactolisib
0.0047
uM
 Saracatinib
0.2138
uM
 2 1843 4186 5189 0.7315
BT-20 Dactolisib
0.0047
uM
 Saracatinib
0.3704
uM
 2 1843 4145 5189 0.7185
BT-20 Dactolisib
0.0047
uM
 Saracatinib
0.6415
uM
 2 1843 4139 5189 0.7193
BT-20 Dactolisib
0.0047
uM
 Saracatinib
1.1111
uM
 2 1843 4207 5189 0.7365
BT-20 Dactolisib
0.0047
uM
 Saracatinib
1.9245
uM
 2 1843 3467 5189 0.5266
BT-20 Dactolisib
0.0047
uM
 Saracatinib
3.3333
uM
 2 1843 3133 5189 0.4264
BT-20 Dactolisib
0.0047
uM
 Trametinib
0.1235
uM
 2 1843 3235 5189 0.4568
BT-20 Dactolisib
0.0047
uM
 Trametinib
0.3704
uM
 2 1843 3012 5189 0.3892
BT-20 Dactolisib
0.0047
uM
 Trametinib
1.1111
uM
 2 1843 2679 5189 0.2847
BT-20 Dactolisib
0.0047
uM
 Trametinib
3.3333
uM
 2 1843 2697 5189 0.2890
BT-20 Dactolisib
0.0137
uM
0
uM
 2 1843 3321 5189 0.4826