Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 3 of 3: Calculated dose-response metrics. - Dataset (ID:20258)
Data Columns
Download: Excel (XLSX), Comma-separated (CSV)
- 20 Data Columns
| Name | Description | Display Name | Data Type | Unit | Precision | Readout Type | Replicate | Comments |
|---|---|---|---|---|---|---|---|---|
| cell | Cell reagent | Cell | cell | |||||
| smallMolecule | Small molecule perturbagen | Small Molecule | small_molecule | |||||
| replicate | Replicate | Numeric | 0 | |||||
| seedingDensity | Seeding Density | Numeric | 2 | |||||
| iC50 | Small molecule concentration at which the treated cell count is 50% of the control cell count (from relative cell count dose-response curve) | IC50 | Text | uM | ||||
| eC50 | Small molecule concentration that results in 50% efficacy (from relative cell count dose-response curve) | EC50 | Text | uM | ||||
| emax | Relative cell count at the highest tested small molecule concentration (from relative cell count dose-response curve) | Emax | Numeric | 4 | ||||
| einf | Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the relative cell count dose-response data | Einf | Numeric | 4 | ||||
| iCHillCoefficient | Maximal slope of the relative cell count dose-response curve | IC Hill Coefficient | Numeric | 4 | ||||
| iCAUC | Area under the curve over the range of concentrations tested (from relative cell count dose-response curve) | IC_AUC | Numeric | 4 | ||||
| iCCurveFit | Formula for the sigmoidal curve fit to the relative cell count dose-response data | IC Curve Fit | Text | |||||
| iCr2 | r^2 for the sigmoidal curve fit to the relative cell count dose-response data | IC r2 | Text | |||||
| gR50 | Small molecule concentration at which GR(c)=0.5 (from GR dose-response curve) | GR50 | Text | uM | ||||
| gEC50 | Small molecule concentration that results in 50% efficacy (from GR dose-response curve) | GEC50 | Text | uM | ||||
| gRmax | Normalized growth inhibition rate at the highest tested small molecule concentration (from GR dose-response curve) | GRmax | Numeric | 4 | ||||
| gRinf | Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the GR dose-response data | GRinf | Numeric | 4 | ||||
| gRHillCoefficient | Maximal slope of the GR dose-response curve | GR Hill Coefficient | Numeric | 4 | ||||
| gRAOC | Integral of GR(c) over the range of concentrations tested (from GR dose-response curve) | GR_AOC | Numeric | 4 | ||||
| gRCurveFit | Formula for the sigmoidal curve fit to the GR dose-response data | GR Curve Fit | Text | |||||
| gRR2 | r^2 for the sigmoidal curve fit to the GR dose-response data | GR r2 | Text |
- 20 Data Columns